diff --git a/web/src/hotkey.js b/web/src/hotkey.js
index 40eda88464..e2c1806518 100644
--- a/web/src/hotkey.js
+++ b/web/src/hotkey.js
@@ -123,6 +123,7 @@ const keydown_either_mappings = {
 const keypress_mappings = {
     42: {name: "star_deprecated", message_view_only: true}, // '*'
     43: {name: "thumbs_up_emoji", message_view_only: true}, // '+'
+    61: {name: "upvote_first_emoji", message_view_only: true}, // '='
     45: {name: "toggle_message_collapse", message_view_only: true}, // '-'
     47: {name: "search", message_view_only: false}, // '/'
     58: {name: "toggle_reactions_popover", message_view_only: true}, // ':'
@@ -967,6 +968,23 @@ export function process_hotkey(e, hotkey) {
             reactions.toggle_emoji_reaction(msg.id, canonical_name);
             return true;
         }
+        case "upvote_first_emoji": {
+            // '=': If the current message has at least one emoji
+            // reaction, toggle out vote on the first one.
+            const message_reactions = reactions.get_message_reactions(msg);
+            if (message_reactions.length === 0) {
+                return true;
+            }
+
+            const first_reaction = message_reactions[0];
+            if (!first_reaction) {
+                // If the message has no emoji reactions, do nothing.
+                return true;
+            }
+
+            reactions.toggle_emoji_reaction(msg.id, first_reaction.emoji_name);
+            return true;
+        }
         case "toggle_topic_mute":
             muted_topics_ui.toggle_topic_mute(msg);
             return true;
diff --git a/web/tests/hotkey.test.js b/web/tests/hotkey.test.js
index f694bffd82..b1545e3177 100644
--- a/web/tests/hotkey.test.js
+++ b/web/tests/hotkey.test.js
@@ -358,6 +358,9 @@ run_test("misc", ({override}) => {
 
     assert_mapping("@", compose_actions, "reply_with_mention");
     assert_mapping("+", reactions, "toggle_emoji_reaction");
+    // Without an existing emoji reaction, this next one will only
+    // call get_message_reactions, so we verify just that.
+    assert_mapping("=", reactions, "get_message_reactions");
     assert_mapping("-", condense, "toggle_collapse");
     assert_mapping("r", compose_actions, "respond_to_message");
     assert_mapping("R", compose_actions, "respond_to_message", true);